Progynova 2mg vs 1mg, Which Estradiol Dose is Right for HRT?

Progynova (estradiol valerate) comes in two oral strengths: 1mg and 2mg. Both contain the same active ingredient but are prescribed for different stages of treatment.

Progynova 1mg: Starting Dose

The 1mg tablet is typically the starting dose for: - Perimenopausal women beginning HRT - Gender-affirming feminising hormone therapy (low-dose initiation) - Maintaining estrogen levels after initial stabilisation

Progynova 2mg: Therapeutic Dose

The 2mg tablet is used when: - Higher estrogen replacement is needed for full menopausal symptom relief - IVF/ART cycles require endometrial preparation - Gender-affirming HRT requires higher systemic estrogen levels

Key Differences at a Glance

Feature | Progynova 1mg | Progynova 2mg | Common use | Low-dose HRT, maintenance | Full-dose HRT, IVF prep | | Dosing frequency | Once or twice daily | Once daily | Suitable for | Early perimenopause, trans femme initiation | Established menopause, IVF protocols

Important Note

Always follow your prescriber's dosing instructions. Doses are adjusted based on blood estradiol levels, symptom response, and treatment goals. Fertimeds supplies both Progynova 1mg and 2mg tablets at wholesale pricing for clinics, pharmacies, and registered resellers.