Valsartan / Sacubitril Tablet

What is valsartan sacubitril tablets?

Valsartan sacubitril tablets have two active ingredients in one tablet, sacubitril and valsartan, made for people managing heart failure. This is not a single-drug tablet. It is a fixed combination, and that is exactly what makes valsartan sacubitril tablets different from taking either drug on its own. Doctors prescribe valsartan sacubitril tablets for adults whose heart muscle has weakened and is no longer pumping the way it should. It is taken by mouth.

Which heart conditions does this tablet treat?

This tablet is used mainly for long-term heart failure in adults, when the heart's pumping ability has dropped below normal. People living with this condition often deal with breathlessness on light activity, tiredness that doesn't go away with rest, and swelling around the ankles and legs because the heart can't move blood around the body efficiently. Valsartan sacubitril tablets don't reverse heart failure, but they ease the strain on the heart and can cut down how often symptoms flare up badly enough to need hospital care. It's usually added alongside other heart failure treatments a doctor has already started, rather than being the very first thing tried.

How does sacubitril valsartan work once swallowed?

Sacubitril blocks an enzyme called neprilysin. Normally this enzyme breaks down natural substances in the body that relax blood vessels and help push out excess salt and fluid. When neprilysin is blocked, those substances stay active longer, so blood vessels open up and fluid buildup around the lungs and legs eases off. Valsartan works differently, it stops a hormone called angiotensin II from acting on blood vessels, which stops those vessels from tightening. Put together, sacubitril and valsartan take pressure off the heart from two separate directions, one keeps vessels relaxed chemically, the other blocks the hormone that would otherwise narrow them.

What strengths does valsartan sacubitril tablets come in?

The numbers on a strip refer to the combined amount of both active ingredients in that tablet. The starting point for many people is the sacubitril valsartan tablet 24 26 mg strength, often used for someone new to the medicine or someone with kidney or liver concerns where a doctor wants to go slow. From there, the range moves up to sacubitril valsartan tablets 50 mg, and higher again to sacubitril valsartan tablets 100 mg once the body has adjusted to the lower strengths. Every strength delivers both sacubitril and valsartan together, there is no version of this product with just one of the two.

What side effects come with valsartan sacubitril tablets?

Most people notice something mild before anything serious, and the two most common complaints are dizziness and tiredness.

• Dizziness or feeling lightheaded, especially when standing up quickly 
• Tiredness in the first stretch of treatment, which tends to ease once blood pressure stabilizes.
• Mild cough
• Higher potassium levels showing up on blood tests
• Low blood pressure symptoms such as feeling faint

Who should not take valsartan sacubitril tablets?

Do not take valsartan sacubitril tablets if you are pregnant or trying to become pregnant, since the valsartan component can harm an unborn baby. This tablet should not be taken together with an ACE inhibitor, and anyone switching from an ACE inhibitor needs a gap of at least 36 hours between stopping one and starting the other, because taking them close together raises the risk of serious swelling reactions. Tell your doctor about any history of kidney disease, liver disease, or a past reaction of swelling to ACE inhibitors or ARBs. People taking potassium supplements, salt substitutes, or lithium should mention this too, since valsartan sacubitril tablets can push potassium levels higher than normal. Keep the strip stored at room temperature, away from damp bathroom cabinets, and don't pop tablets out until you're about to take them.

What does valsartan sacubitril tablets cost at Fertimeds?

Fertimeds lists valsartan sacubitril tablets starting at , and pricing varies by strength, so the sacubitril valsartan tablets price for a 24 26 mg pack differs from the sacubitril valsartan tablets 100 mg price on the higher strip. Anyone asking about sacubitril valsartan tablets 50 mg uses is usually already partway through treatment, moving up from the starting strength as their doctor adjusts things. This tablet needs a prescription and can be ordered through Fertimeds where local rules allow it.