Duphaston 10mg tablet

What is Duphaston 10mg tablet?

Duphaston 10mg tablet contains dydrogesterone as its active ingredient. Dydrogesterone is a synthetic progestogen closely related to the natural progesterone the female body produces. It supports the uterine lining and prepares the womb for pregnancy. The tablet is taken by mouth at a fixed daily dose.

What is it used for?

Duphaston 10mg is used for conditions related to progesterone deficiency in women. Doctors prescribe it for irregular menstrual cycles, painful periods, endometriosis, and to support early pregnancy. It is also used in recurrent miscarriage and premenstrual syndrome. One drug, two main purposes — cycle regulation and pregnancy support.

How does it work?

Dydrogesterone binds to progesterone receptors in the lining of the uterus. This causes the endometrium to develop properly so it is ready to receive a fertilised egg. At the doses commonly prescribed, it does not suppress ovulation. Hormone balance is maintained without interfering with the natural cycle in most cases.

In what strengths is it available?

Duphaston comes in the 10mg strength. This is the dose used across most of the conditions it treats. Your doctor will adjust how many tablets you take per day depending on your condition. Strength stays fixed. Dosing frequency changes with the indication.

How to take it / dosage

Take Duphaston 10mg by mouth with a glass of water. Your doctor will tell you how many times a day to take it and on which days of your cycle. For conditions like threatened miscarriage, it may be taken continuously for several weeks. Do not stop suddenly without speaking to your doctor first.

Many patients ask whether it can be taken without food. It can. Taking it at the same time each day gives the best result.

What are the side effects?

Some side effects can occur when taking dydrogesterone. Minor effects are more common. Serious effects are rare but should not be ignored.

Common side effects:

• Nausea
• Headache
• Breast tenderness or swelling
• Mild abdominal discomfort
• Irregular spotting between periods

Less common or serious:

• Skin rash or allergic reaction
• Unusual vaginal bleeding
• Swelling of the face, lips, or tongue
• Jaundice 

Who should not take it?

Duphaston 10mg is not suitable for everyone. Women with known or suspected hormone-sensitive cancers should not take it. Those with a history of liver problems or unexplained vaginal bleeding should speak to a doctor before starting. Anyone with a known allergy to dydrogesterone or related compounds should also avoid it. Always check with your doctor before starting any hormonal treatment.

• Store tablets at room temperature, away from direct sunlight and moisture. 
• Do not store in the bathroom dydrogesterone tablets can be sensitive to damp conditions.
• Duphaston 10mg tablet is available to order at Fertimeds.